When two freshmen pledges are accepted into the biggest party frat on campus (ALPHA HOUSE), they think they have it all. That is, until the assistant dean forces the Alphas to share their house with a sorority or face expulsion from school. Not wanting to see their lifelong dream of becoming Alphas destroyed, the pledges convince the other members of the house to take back what's theirs, waging an epic battle of the sexes to fight for their right to party.

If you mixed Ferris Bueller in a blender with Alvy Singer (Woody Allen in "Annie Hall") and Larry David, the result would be SAM BAUM (Josh Gad). He's a lovable, quirky, neurotic NY native, living in LA with his beautiful girlfriend, Sammy (Kristen Ruhlin). A girl he knows how lucky he is to have in his life, since she was previously married to John: a, tall, fit, gorgeous, extremely successful Harvard med school graduate, who she's remained cordial with. Before Sammy, Sam hasn't had much success, romantically. He's an emerging filmmaker with one feature film under his belt that nobody's heard of. And she's an aspiring actress, aching for her big break, which may never come, unless Sam offers her the female lead in his next project, which he does... the night before one of the hottest, most in demand actresses working today, Kim Powers (Hilary Duff), expresses interest in playing the role. Sam wears his heart on his sleeve and has always been honest with Sammy, but now he's caught in ...